People outside sample beers at Palmetto Brewing in Charleston, SC.

UPDATE: Check out our new 2023 Best Cities to Live in the U.S. list.

#77. Charleston

The oldest city in South Carolina, Charleston is known for its beautiful architecture and vibrant performing arts scene that includes America’s first professional theater (Dock Street Theatre). The College of Charleston and The Citadel give the community a college-town feel, and eight microbreweries are now doing brisk business. Among them are Holy City Brewing and Palmetto Brewery that issues brands like Espresso Porter and Charleston Lager.

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