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Businesses in Tyler, TX

Area economy stays diverse and dynamic.

By Cary Estes on November 17, 2015

The Texas Allergy, Indoor Environment and Energy Institute in Tyler, TX
Tyler / Antony Boshier

Several factors make Tyler’s economy successful, including low unemployment, affordable cost of living, easy interstate access, abundant internet connectivity and high-quality lifestyle amenities. Combine all that with strong support from the Tyler Area Chamber of Commerce, and you’ve got an attractive business climate. Here are some highlights:

Tyler Economic Development Council

The Tyler Economic Development Council has worked on nearly 175 projects since it formed in 1989, and during that time the TEDC has assisted in the creation or retention of about 20,000 jobs and helped generate more than $700 million in new investment in Tyler. Helping to make Tyler attractive to businesses are factors such as a skilled workforce, three colleges and low taxes, while the community also has many arts attractions and recreation options.

Health Care Industry

Tyler is a major regional medical hub that serves the city’s 100,000 residents as well as seven surrounding East Texas counties. The city is home to four hospitals – East Texas Medical Center, Texas Spine & Joint Hospital, CHRISTUS Mother Frances Hospital and UT Health Northeast. In addition, Tyler Junior College recently constructed a new TJC Nursing and Health Sciences building, and UT Tyler is now enrolling students in its new UT Tyler Pharmacy School.

In early 2017, health care organization Fresenius Medical Care North America opened an $11.2 million medical business office support facility at the corner of SSW Loop 323 and Earl Campbell Parkway, which will ultimately feature 300-350 new jobs. Meanwhile, Centene Corp., which processes Medicare and Medicaid claims for more than 3 million members nationwide, moved into Tyler in late 2013 and has already expanded its facility on Earl Campbell Parkway.

Other Major Industries & Employers

Besides the aforementioned medical facilities and health-care organizations, Tyler also has robust economic sectors in education, food production, manufacturing, retail and technology. Some of the city’s top employers include Brookshire’s, John Soules Foods, Southside Bank, Suddenlink, Target Distribution Center, Trane, Tyler Independent School District, Tyler Pipe and Walmart.


Several major highways pass through Tyler, including Interstate 20 that continues east all the way to South Carolina. Other key roadways through the city are U.S. Highway 69 and State Highway 64. Tyler Pounds Regional Airport is another business asset, with nonstop commercial service to Dallas/Fort Worth and Bush Intercontinental-Houston. The airport accommodates more than 150,000 passengers annually. For companies wanting to ship goods by rail, Union Pacific serves Tyler and East Texas.

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