University of Colorado"“Boulder in Boulder, CO

UPDATE: Check out our new 2023 Best Cities to Live in the U.S. list.

#1. Boulder

There’s no better way to describe Boulder than to say it is the perfect storm for entrepreneurial success. Thanks in large part to the University of Colorado’s presence, there’s a culture of innovation, here, unlike anywhere else. Combine that with all the support of small business efforts (the Boulder SBDC, the Economic Vitality Program, etc.), and you have our 2016 Best City for Entrepreneurs.

Business Growth (2011-2015): 14%

Employment Growth (2011-2015): 18%

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