UPDATE: Check out our new 2023 Best Cities to Live in the U.S. list.

#43. Iowa City

Iowa City isn’t just a great place to start a business, it’s also just a great place to live, and has been included on our 100 Best Places to Live list three years in a row, now. The John Pappajohn Entrepreneurial Center offers excellent collaboration opportunities for Iowa City innovators. Also available are I-Envision, the Iowa Small Business Development Center, and the Jacobson Institute for Youth Entrepreneurship.

Business Growth (2011-2015): 10%

Employment Growth (2011-2015): 10%

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