This city on the rise ranked number 1 on our Top 100 Best Places to Live list in 2016. Rochester, home to Mayo Clinic, is in an era of growth, making it a great spot for entrepreneurs. In this city, the living’s easy, ranking in the top 10 for household income growth, affordable housing and jobs. Other notable rankings include a top 15 ranking for high wage job growth, top 20 ranking for creative class workers and top 10 ranking for commute times. Rochester has also been featured on our Top 10 Most Affordable Places to Live.