UPDATE: Check out our new 2023 Best Cities to Live in the U.S. list.

#69. Greenville

In the northwest portion of South Carolina is Greenville, recognized as one of the fastest-growing cities in the nation. A strong economy is led by sectors such as automotive, aviation, health care, IT and manufacturing, and the city’s cultural scene features a half-dozen breweries. They include Brewery 85 as well as Quest Brewing Co. that offers our choice: the Golden Fleece Belgian Pale Ale.

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